After a quiet first period, second-half goals from Son Heung-Min, Jan Vertonghen and Fernando Llorente gave Spurs a resounding win at Wembley.
The north Londoners will now take a three-goal bumper to the intimidating Signal Iduna Park in three weeks time.
Over 70,000 fans were in attendance, with several jubilant Spurs fans and a small proportion of Dortmund’s Yellow Wall making their feelings known.
But what did goalscorer’s Son Heung-Min and Jan Vertonghen, Spurs boss Mauricio Pochettino and Dortmund’s England winger Jadon Sancho make of the game?
“It was at Wembley too in the Champions League so it was special”
Vertonghen, who scored his first ever Champions League goal to double Spurs lead with a fine finish, admitted it was a “special” night for him.
“They dropped off a bit then that early goal in the second half helped. We had the confidence to keep going,” the Belgian said.
“It was [my first goal] since the first game this season and I had to wait for goal line technology then so I was happy that I could just go [to celebrate this time]!
“It was at Wembley too in the Champions League so it was special. It was one of those nights.”
South Korean forward Son, who scored the opener with a volley from Vertonghen’s pin-point cross, was full of admiration for his team-mate.
Son said: “Jan Vertonghen is technically unbelievable and can play in any position. I am very happy for him, he deserved it.
“One goal and an assist! The timing of the first goal was very important, the cross was unreal, I didn’t have to do anything, just touch the ball.
“It’s not finished, we have to focus on the second game too. Harry or Dele are very important for us, but we have players who can come in and do well.”
Spurs boss Pochettino described the match as a game of two halves, but the Argentine believes his side’s confidence shone through in second to help his team pull away.
“It was a fantastic second half. The first half was difficult. It was a difficult game from the beginning. It was difficult to find what the best position was in both directions.
“When we had the ball we struggled to play in the way we wanted to play. The team started to feel comfortable, then we scored. And afterwards we played with more confidence.
“We have a lot of talented players. We have an unbelievable squad. I am happy with all the players. The only problem is that we can only play 11 and not 22.”
18-year-old winger Sancho had a quiet night on his return to his native England, but the ex-Manchester City youngster admitted he was just pleased to be home.
“I don’t have any words for the second half. We tried our best but they scored and were the better team.
“In the first half we played really well. We dropped a bit and lost focus. We need to keep focused for the whole game.
“I am happy that I am home and I hope I gave the audience something they never knew about me. We will keep believing we can score more than them and hopefully we can get through to the next round.”