The 50-year-old officiated his first game in 2000 and has gone on to issue a record 99 red cards in the Premier League in his career.
Many fans believed he has been waiting for a big game to give out his centenary sending-off, and that game could come today during Manchester City vs Chelsea.
The match is of magnificent magnitude between two top sides battling for different reasons.
City are chasing down Liverpool for the Premier League title, narrowing the gap to put pressure of Jurgen Klopp’s men.
While Chelsea are aiming to finish in the top four and achieve Champions League football next season.
But the game was effectively over after just 18 minutes after the Etihad side breezed into a 3-0 lead.
Raheem Sterling and Sergio Aguero scored after some shocking defending from the visitors.
And Ilkay Gundogan scored not long after to make it 4-0 before half-time.
With the match over, it was Dean’s time to shine when in the second half Cesar Azpilicueta fouled Sterling in the box.
In typical Dean fashion, he dramatically pointed to the penalty spot after a short delay.
And fans were quick to jump onto social media to react to the Wirral-born ref.
One said: “Kings stay Kings. Absolute top level stuff by Mike Dean. Peak.”
Another said: “Mike Dean with the most dramatic pointing to the penalty spot that I’ve ever seen.”
While this fan tweeted: “Mike Dean pointing to the spot with sauce.”